Amiodarone Verticillata - Whorl Keratopathy (Video)


length: 28 seconds

This video shows a cornea with amiodarone verticillata deposits. You can see these as a whorl pattern - the entity is also called whorl keratopathy or hurricane keratopathy. These deposits are benign, difficult to see, and rarely (if ever) have any visual significance.

Drugs that can cause this pattern: CACTI Mneumonic: chloroquine, amiodarone, chlorpromazine, tamoxifen, indomethacin.

In addition, you can presumably get a similar pattern with amodiaquine, meperidine, and with Fabry’s disease.

Download this video for powerpoint

download.gifTo download this video, right click on a link below and choose “Save Target As…”

but.gifverticillata.wmv (3.5 meg, Windows video file)
but.gifverticillata.wmv (Quicktime format coming soon)

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Thumbnails (click to enlarge photo)

cornealverticillata.jpg whorlkeratopathy.jpg amiodaroneverticillata.jpg


Comments and Feedback
5 Comments »


You are the best teacher!!!!!!!

Love all your work here and with opthobook.

Thank you for sharing your knowledge with us in such a good way.

Comment by Sarah — July 4, 2009 @ 5:49 pm


I completely agree with Sara, this site is awsome, Could have a Spanish version?.
Hi from Peru

Comment by Javier — August 25, 2009 @ 11:10 am


this is so great!

Comment by khine nwe ni — May 21, 2010 @ 9:58 pm


I have Neurotrophic Keratipathy in both eye would like to know other people that have this

Comment by KEISHA JOHNSON — November 15, 2010 @ 5:41 pm


Sorry Dr. Root! Could you answer my question?
How to carry out the differential diagnoses of amiodarone verticillata whorl keratopathy and Cogan’s (map-dot-fingerprint) dystrophy?

Thanks in advance

Comment by eyedoc — March 1, 2011 @ 7:40 pm


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